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Managing MAD Side Effects in Sleep Apnea Patients

Managing MAD Side Effects in Sleep Apnea Patients

Sleep apnea patients using mandibular advancement devices often experience side effects that can impact treatment success. This article draws on expert recommendations to help clinicians address common complications and maintain patient comfort throughout therapy. Learn practical strategies for monitoring bite changes and preventing long-term orthodontic issues in your patients.

Use Daytime Aligners to Confirm Bite Stability

When caring for patients using mandibular advancement appliances, the type of appliance determines the need for additional treatment. Removable mandibular anterior repositioning appliances, like those used for sleep apnea, can place the patient into an edge-to-edge anterior bite or anterior crossbite. These underbites can cause discomfort, increased tooth wear, difficulty chewing, and poor aesthetics. Thus, if the patient wants to continue using the appliance rather than using a CPAP machine, morning/daytime aligners are a good option for bite maintenance. These aligners sometimes require class II elastic wear if aligner wear alone does not solve the problem. This can counteract the nighttime anterior mandibular bite movement that can occur with sleep apnea appliances.

Younger patients wearing bonded mandibular advancement appliances (MARA, Herbst) see similar bite changes, but these are desirable and the purpose of the appliance. In patients who are uncomfortable when starting one of these appliances, we recommend removing the activation arms at first or setting the appliance to the minimal baseline activation. Daytime aligners are difficult to use in conjunction with these elaborate intraoral appliances and, therefore, are not usually recommended.


For those with tight muscles, some light exercises are available as an optional adjunct. Some light, not forceful, movements can be helpful-simple opening, lateral movements, and gentle stretching sometimes help with muscle tension. These exercises are often more helpful in the first few weeks of appliance use, gradually becoming unnecessary as the patient acclimates to the appliance.


As far as monitoring is concerned, intervals of four to eight weeks can be helpful, followed by 6 or 12-month intervals. Patient education or remote monitoring photos can reduce the number of in-office visits.

The most obvious sign of good progress in acclimation is bite stability. Limited or no morning discomfort and a normal centric occlusion bite without shifting (ideally class I if the patient was class I before starting appliance use) from appointment to appointment suggests a stable process without major ill effects. Bite observation and patient education help determine if further intervention will be required. Mandibular advancement devices can therefore be effective tools if their side effects are well controlled.

Scott Cardall
Scott CardallOwner Orthodontist, Orem Orthodontics

Set Baselines and Schedule Early Checkups

One strategy I consistently use is establishing a very structured follow-up and baseline comparison protocol. Before delivering a mandibular advancement device, I document the patient's baseline occlusion, overjet/overbite, and TMJ status with photos, digital scans, and a symptom review.

I schedule early and frequent follow-ups—typically at 2 weeks, 6 weeks, and then every 3-4 months during the first year—to monitor for bite changes or TMJ soreness. At each visit, I assess occlusal contacts, mandibular range of motion, joint tenderness, and patient-reported symptoms such as morning bite shifts or jaw fatigue.

Indicators that the strategy is working include stable occlusal contacts compared to baseline, resolution or absence of TMJ discomfort, and the patient reporting that their bite feels normal shortly after device removal in the morning. If I detect early changes, I intervene promptly with appliance adjustment, reduced advancement, morning repositioning exercises, or a bite-repositioning device to minimize long-term side effects.

Tune Vertical Height for TMJ Protection

Too much bite opening increases leverage on the jaw joint and can raise joint and muscle load. Using the smallest effective opening limits jaw rotation and reduces stress on the joint. Thin designs and low bite pads can give airway help without over-opening.

Measuring natural space between teeth helps set a comfortable starting gap. Ongoing checks for clicking, soreness, or limited motion allow timely changes to the opening. Ask your clinician to tune vertical height for comfort and joint health today.

Choose Adjustable Designs with Morning Reposition Tools

Adjustable mandibular advancement devices allow small step changes in jaw position, which helps protect the bite. Gradual changes lower the risk of tooth movement by avoiding big jumps forward. Features that keep the device stable also help spread forces evenly across the teeth.

A morning repositioning tool can help the bite return to normal after nightly use. Regular checks of bite contacts and jaw motion allow early correction if changes appear. Ask a qualified sleep dentist about an adjustable design and a bite protection plan today.

Clear Nasal Blockage to Reduce Jaw Strain

High nasal resistance forces mouth breathing, which makes the jaw work harder against the device. Clearing the nose reduces the suction effect that pulls the jaw down and forward. Simple steps like saline rinses, allergy care, and humid air can improve flow.

When a blockage is suspected, an ENT visit can check for swollen tissue or a bent septum. Better nasal airflow often lowers clenching and morning soreness. Book an airway check and start a nose care plan today.

Boost Oral Moisture to Prevent Dryness

Dry mouth and throat irritation can rise with oral devices and may lead to gum and tooth problems. Good room humidity and steady water intake help keep tissues moist and comfortable. A bedside humidifier or built-in humidification with combo therapy can reduce dryness.

Vented designs let air move gently and can lessen drooling and lip soreness. Oral moisturizing gels before bed may also improve comfort and lower friction. Make a moisture plan with your provider and adjust your appliance setup today.

Adopt Side Sleep to Ease Device Force

Sleeping on the side lowers airway collapse compared with lying on the back. With fewer events, the device can be set to less forward movement, which eases pressure on teeth and the jaw joint. Positional training tools and pillow methods can help keep the body off the back through the night.

A neutral neck position also helps keep the airway open without extra jaw force. Tracking sleep positions with a wearable or an app can confirm progress and guide changes. Try a side-sleep plan and review device settings with your provider today.

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